Last edited by Mazurn
Thursday, July 30, 2020 | History

2 edition of Optimization and design of granulation technologies for high-value added industries found in the catalog.

Optimization and design of granulation technologies for high-value added industries

Powder & Bulk Solids Conference/Exhibition (1997 Rosemont, Il.)

Optimization and design of granulation technologies for high-value added industries

Powder & Bulk Solids Conference/Exhibition, May 5-8, 1997, Rosemont Convention Center, Rosemont, IL

by Powder & Bulk Solids Conference/Exhibition (1997 Rosemont, Il.)

  • 32 Want to read
  • 10 Currently reading

Published by E&G Associates in Nashville, TN .
Written in English

    Subjects:
  • Granulation -- Congresses,
  • Bulk solids,
  • Powders -- Congresses,
  • Bulk solids handling -- Congresses

  • Edition Notes

    StatementBryan Ennis.
    GenreCongresses
    ContributionsEnnis, Bryan
    Classifications
    LC ClassificationsTA"418.78"I58"1997"T-6
    The Physical Object
    Pagination2 v. :
    ID Numbers
    Open LibraryOL21660849M

      Continuous Granulation Technology Trends. of the requirements for continuous solids processing is the implementation of real-time online sensing for control and optimization in order to ensure its safety and efficiency. 5,6 However, Latest Breaking News From Orthopedic Design & Technology. The Third Edition presents all pharmaceutical industry personnel and those in academia with critical updates on the recent advances in granulation technology and changes in FDA regulatory guidelines. Addressing precisely how these recent innovations and revisions affect unit operation of particle generation and granulation, this text assists.

    Abstract. The complexity of large-scale mechanical optimization problems is partially due to the presence of high-dimensional design variables, the nature of the design variables, and the high computational cost of the finite element simulations needed to evaluate the fitness of candidate solutions. The fractional factorial design showed that the nozzle air pressure was also important. As the target values for the granule yield (between 75 and μm) and the geometric mean granule size (between and μm) were reached during the screening experiments, further optimization .

    Control (MPC) technology to a Calcium Ammonium Nitrate (CAN) granulation process. Although APC is a common tool in many process industries, like refining and petro-chemical, the technology is less introduced and common in fertilizer industry and only very few applications can be found for granulation . Integrating the basic principles and industrial practices of pharmaceutical granulation production, this book discusses technologies and demonstrates cost-effective approaches to manufacturing solid-dosage forms with content uniformity and consistent physical properties while complying with regulatory requirements. Specialists from pharmaceutical companies, academia, and the U.S. Drug Reviews: 1.


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Optimization and design of granulation technologies for high-value added industries by Powder & Bulk Solids Conference/Exhibition (1997 Rosemont, Il.) Download PDF EPUB FB2

Wet granulation is a process frequently employed during the manufacture of oral solid dosage forms. The objective is to convert the often fine and cohesive active ingredient and excipients, into more uniform, free-flowing granules that are optimized for downstream processing.

Granulation is the process of forming grains or granules from a powdery or solid substance, producing a granular is applied in several technological processes in the chemical and pharmaceutical industries. Typically, granulation involves agglomeration of fine particles into larger granules, typically of size range between and mm depending on their subsequent use.

Process Analytical Technology (PAT) regulatory issues in granulation; In addition, all chapters in the Handbook of Pharmaceutical Granulation Technology explore the fundamentals of powder characterization, granulation, and state-of-the-art technologies, modeling, application of expert systems, and manufacturing s: 1.

Granulation. Granulation was monitored using an in-line DFF sensor type P by Lenterra Inc. The probe was installed from the granulator lid using an available ISO KF flange (as shown in Fig. 9 of Chapter 15) in such a way that the tip of the probe was cm above the top of the granulator blade and cm off the blade rotation axis.

Granules are produced to enhance the uniformity of the API in the final product, to increase the density of the blend so that it occupies less volume per unit weight for better storage and shipment, to facilitate metering or volumetric dispensing, to reduce dust during granulation process to reduce toxic exposure and process-related hazards, and to improve the appearance of the product ♥ Book Title: Handbook of Pharmaceutical Granulation Technology, Third Edition ♣ Name Author: Dilip M.

Parikh ∞ Launching: Info ISBN Link: ⊗ Detail ISBN code: ⊕ Number Pages: Total sheet ♮ News id: Bu1MBgAAQBAJ Download File Start Reading ☯ Full Synopsis: "The Third Edition presents all pharmaceutical industry personnel and.

Process Systems Engineering for Pharmaceutical Manufacturing: From Product Design to Enterprise-Wide Decisions, Vol covers the following process systems engineering methods and tools for the modernization of the pharmaceutical industry: computer-aided pharmaceutical product design and pharmaceutical production processes design/synthesis; modeling and simulation of the.

Granulation, the process of particle enlargement by agglomeration technique, is one of the most significant unit operations in the production of pharmaceutical dosage forms, mostly tablets and capsules. Granulation process transforms fine powders into free-flowing, dust-free granules that are easy to compress.

Nevertheless, granulation poses numerous challenges due to high quality requirement. is a platform for academics to share research papers. During wet granulation, liquid is added to the powder mix and distributed as films around and between the particles. There are three states of water distribution between particles.

At low moisture levels, the pendular state, particles are held together by surface tension forces of the liquid/air interface and the hydrostatic suction pressure in. Granulation Technology, Inc.

is a chemical and pharmaceutical manufacturing and distribution company that has been in business since successfully serving small to Fortune companies. GTI is a FDA GDUFA listed facility. It is a fully functio sq. cGMP facility. DEA Registered to handle Class II - V controlled subtances.

Recent progress in dry granulation. Dry granulation could be achieved either by roller compaction or by slugging. The two different types are illustrated in the schematic diagram Fig.

has not been much progress in the dry granulation technique and technology in comparison to wet granulation, except for one important innovation known as pneumatic dry granulation technology.

Within the pharmaceutical industry, ongoing efforts to move from batch tabletting to continuous manufacturing suites are intensifying the need for improved granulation control.

High shear granulation demands robust, continuous particle size measurement at high solids loadings within a. Materials and methods:The process of granulation by fluidized bed granulation technology was used to prepare eight formulations (F1-F8) using various concentrations of binders PVP K, PVP K   Objective functions for system optimization and open-loop optimal control The objective function for system optimization of batch granulation is Min {j-wlMp(tf)} Sd,Bd,Xw tf (26) S.t.

equation (11) The objective function for batch granulation with the binder spray rate as the only manipulated variable is given by Min{-WIMp(tf)+W2fo tfRwdt} Rw.

An experimental factorial design (2̂4) was applied to include process variables and the drug load. Ribbon properties, i.e.

relative density, tensile strength and Young's modulus and granules. Granulation Technology is located in Fairfield, New Jersey. This organization primarily operates in the Pharmaceutical Preparations business / industry within the Chemicals and Allied Products sector.

This organization has been operating for approximately 23 years. Granulation Technologies There are a huge number of various kinds of newly developed technologies which are suitable for the processing and production of granules of desirable shapes and sizes, although the granule size used in the pharmaceutical industries ranges between to mm.

The granulation technologies most likely to be used are: 1. 8 Pharmaceutical Technology TABLETING & GRANULATION The Granulation Process Basic Technologies for Tablet Making Michael Michael D.

Tousey is the technical services director and owner of Dorado International, Inc., a pharmaceutical equipment and training company, Wilkerson Drive, Westminster, SC   Granulation provides a complete and comprehensive introduction on the state-of-the-art of granulation and how it can be applied both in an academic context and from an industrial perspective.

Coupling science and engineering practices it covers differing length scales from the sub-granule level through behaviour through single granules, to bulk granule behaviour and equipment design.4/5(1).

Design & Optimization of Granulation & Compaction Processes for Enhanced Product Performance Nashville, and “Theory of Granulation: An Engineering Perspective,” in Handbook of Pharmaceutical Granulation Technology, 2nd Ed., Marcel Dekker, Book request.

top. Applying basic theories to industrial practices in pharmaceutical development, this Second Edition explains how new and emerging technologies are utilized in the production of pharmaceutical granulation-demonstrating cost-effective strategies to manufacture solid-dosage forms with consistent physical properties while complying with current regulato.granulation processes.

Ferroalloy producers find the GRANSHOT process attractive due to: High capacity granulation, fully adequate for the needs in ferroalloy production A minimum of metal loss, typically less than % and no formation of dust Repeatable and industrial process due to rugged design and full automation.